Frank van Leth

Associate Professor Health Sciences

Predictive value of the urinary dipstick test in the management of patients with urinary tract infection-associated symptoms in primary care in Indonesia: a cross-sectional study


Journal article


F. Ginting, A. Sugianli, R. L. Kusumawati, I. Parwati, M. D. de Jong, C. Schultsz, F. van Leth
BMJ Open, 2018

Semantic Scholar DOI PubMedCentral PubMed
Cite

Cite

APA   Click to copy
Ginting, F., Sugianli, A., Kusumawati, R. L., Parwati, I., de Jong, M. D., Schultsz, C., & van Leth, F. (2018). Predictive value of the urinary dipstick test in the management of patients with urinary tract infection-associated symptoms in primary care in Indonesia: a cross-sectional study. BMJ Open.


Chicago/Turabian   Click to copy
Ginting, F., A. Sugianli, R. L. Kusumawati, I. Parwati, M. D. de Jong, C. Schultsz, and F. van Leth. “Predictive Value of the Urinary Dipstick Test in the Management of Patients with Urinary Tract Infection-Associated Symptoms in Primary Care in Indonesia: a Cross-Sectional Study.” BMJ Open (2018).


MLA   Click to copy
Ginting, F., et al. “Predictive Value of the Urinary Dipstick Test in the Management of Patients with Urinary Tract Infection-Associated Symptoms in Primary Care in Indonesia: a Cross-Sectional Study.” BMJ Open, 2018.


BibTeX   Click to copy

@article{f2018a,
  title = {Predictive value of the urinary dipstick test in the management of patients with urinary tract infection-associated symptoms in primary care in Indonesia: a cross-sectional study},
  year = {2018},
  journal = {BMJ Open},
  author = {Ginting, F. and Sugianli, A. and Kusumawati, R. L. and Parwati, I. and de Jong, M. D. and Schultsz, C. and van Leth, F.}
}

Abstract

Objective To assess the test characteristics of a urine dipstick test in predicting a positive urine culture in an outpatient setting in Indonesia. Design Cross-sectional study. Setting Two outpatient clinics in Medan, Indonesia. Participants 616 consecutively enrolled participants suspected of having a urinary tract infection. Outcome measures The primary outcome is the estimates of accuracy (sensitivity, specificity, predictive values) where urine culture is the reference test. The secondary outcome is the post-test probability of a positive urine culture. Results The optimal test characteristics were obtained when index test positivity was defined as any leucocyte esterase reaction and/or a nitrite reaction and reference test positivity was defined as a urine culture with a growth of at least 103 colony-forming units/mL (sensitivity: 88.2% (95% CI 81.6 to 93.1), negative predictive value: 93.0% (95% CI 88.9 to 95.9)). The post-test probability of a positive urine culture after a negative urinary dipstick test was 7% in the obstetric/gynaecology clinic and 8% in the internal medicine clinic. Conclusion The use of a urine dipstick test in a rule-out strategy can reduce the need for urine culture and avoid the prescription of (ineffective) antibiotics in a non-urology outpatient setting.