The central objective of this project is to validate, optimize and implement the use of Lot Quality Assurance Sampling (LQAS) as a tool for surveillance of antimicrobial resistance (AMR), and a feasible strategy to timely inform local antimicrobial stewardship activities.

Part 1:
Simulating LQAS-based AMR surveillance using existing data on drug-resistant tuberculosis, and on drug resistance in urinary tract infections (UTI).
2013 - 2020

Part 2:
Validating the strategy against a conventional drug resistance survey in outpatients and inpatients suspected of UTI in 11 sites from 2 islands of Indonesia (Java [Bandung], and Sumatra [Medan]).
2013 - 2020

Part 3:
Implementing LQAS-based surveilance within a One-Health framework.
Within the human domain, the project moves from a static to a dynamic version of LQAS-based AMR surveillance in outpatients suspected of UTI in Burkina Faso and Togo.
Within the veterinary domain, the project introduces a static LQAS-based AMR surveillance at the level of farms under the respsonsibility of a single veterinary in Germany. AMR will be assessed from aggregated faeces collected from trucks that deliver animals to slaughter houses.
2020 - 2024

Funding:
Part 1 and Part 2: Netherlands Academy of Science (KNAW);
Part 3: JPIAMR

Project partners:
Part 1 and Part 2: 

Part 3: